Epitheloid Angiosarcoma of Liver: A Hanging Tumour
Published: September 1, 2020 | DOI: https://doi.org/10.7860/JCDR/2020/44614.13996
Aniruddha Bhosale, Priyanka Ghodekar, Wipula Deshmukh, Shailesh Sable, Bipin Vibhute
1. Junior Consultant and Fellow, Department of Liver Transplant and HPB Surgery, Sahyadri Speciality Hospital, Pune, Maharashtra, India.
2. Junior Consultant, Department of Radio-diagnosis, Sahyadri Speciality Hospital, Pune, Maharashtra, India.
3. Junior Consultant, Department of Radio-diagnosis, Deenanath Mangeshkar Hospital, Pune, Maharashtra, India.
4. Senior Consultant, Department of Liver Transplant and HPB Surgery, Sahyadri Speciality Hospital, Pune, Maharashtra, India.
5. Senior Consultant and Head, Department of Liver Transplant and HPB Surgery, Sahyadri Speciality Hospital, Pune, Maharashtra, India.
Correspondence
Aniruddha Bhosale,
Flat No.16, Takshak Apartments, Nagala Park, Kolhapur, Maharashtra, India.
E-mail: aniruddhabhosale@rediff.com
Primary Epitheloid Angiosarcoma (EA) of liver is an aggressive malignant tumour with poor prognosis irrespective of aggressive surgical resection with or without adjuvant therapy. It constitutes for 0.1-2% of primary malignant tumours of liver and is seen commonly in sixth or seventh decade of life, with male preponderance. It can be asymptomatic or may present with nonspecific symptoms. Lack of pathognomonic features on serological, biochemical and radiological tests, makes it even difficult for an early diagnosis. Despite early surgical removal, EA has very high recurrence rate. Chemotherapy agents (paclitaxel, bevacizumab) and immunomodulators (mTOR inhibitors) have shown some survival benefit and reduction in recurrence rates in recent years as adjuvant therapy.
To the best of our knowledge, a hanging morphological variant of EA of liver has not been reported yet in literature. We report a case of incidentally diagnosed aggressive, hanging variant of EA of liver. Despite early surgical resection and adjuvant, after chemotherapy patient had survival of less than eight months since first presentation.
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